| Date | Location | Result | |
| Nov 04, 2000 | Canyon, TX | Eastern New Mexico 49, West Texas A&M 21 | Box score |
| Oct 28, 2000 | Blackwater Draw, NM | Eastern New Mexico 35, Texas A&M-Kingsville 7 | Box score |
| Oct 21, 2000 | Commerce, Texas | Texas A&M-Commerce 9, Eastern New Mexico 7 | Box score |
| Oct 14, 2000 | Blackwater Draw, NM | Eastern New Mexico 34, Tarleton State 27 | Box score |
| Oct 07, 2000 | San Angelo, Texas | Eastern New Mexico 18, Angelo State 8 | Box score |
| Sep 30, 2000 | Blackwater Draw, NM | Abilene Christian 23, Eastern New Mexico 21 | Box score |
| Sep 23, 2000 | Blackwater Draw, NM | Eastern New Mexico 21, Central Oklahoma 16 | Box score |
| Sep 16, 2000 | Blackwater Draw, NM | Midwestern State 33, Eastern New Mexico 16 | Box score |
| Sep 9, 2000 | Las Vegas, NM | New Mexico Highlands 30, Eastern New Mexico 22 | Box score |
| Sep 02, 2000 | Blackwater Draw, NM | Eastern New Mexico 41, Western New Mexico 6 | Box score |